7H62

THE 1.61 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 5-fluoro-3-methyl-N-[4-pyridin-4-yl-2-(trifluoromethyl)phenyl]-1-benzothiophene-2-sulfonamide

This is a non-PDB format compatible entry.

Summary for 7H62

• Entry DOI: 10.2210/pdb7h62/pdb
• Group deposition: A set of chymase crystal structures for D3R plus two CatG off-target structures (G_1002292)
• Descriptor: Chymase, ZINC ION, 5-fluoro-3-methyl-N-[4-(pyridin-4-yl)-2-(trifluoromethyl)phenyl]-1-benzothiophene-2-sulfonamide, ... (4 entities in total)
• Functional Keywords: human chymase, serine proteinase, chymase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 25564.79

Authors

Banner, D.W.,Benz, J.M.,Schlatter, D.,Wessel, H.P. (deposition date: 2024-04-19, release date: 2025-03-05)

• Primary citation: Markus, R.,Tosstorff, A.; Crystal structures of human Chymase and Cathepsin G; To be published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)