7G8W
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1416193393
Summary for 7G8W
Entry DOI | 10.2210/pdb7g8w/pdb |
Group deposition | ARHGEF2 PanDDA analysis group deposition (G_1002269) |
Descriptor | Transforming protein RhoA, Rho guanine nucleotide exchange factor 2, 4-(5-methyl-1H-pyrazol-4-yl)piperidine, ... (6 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, cytosolic protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 50724.35 |
Authors | Bradshaw, W.J.,Katis, V.L.,Bountra, C.,von Delft, F.,Brennan, P.E. (deposition date: 2023-06-22, release date: 2023-07-12, Last modification date: 2024-05-22) |
Primary citation | Bradshaw, W.J.,Katis, V.L.,Bountra, C.,von Delft, F.,Brennan, P.E. ARHGEF2 PanDDA analysis group deposition To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.939 Å) |
Structure validation
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