7FVO
PanDDA analysis group deposition -- PHIP in complex with Z1435810807
Summary for 7FVO
Entry DOI | 10.2210/pdb7fvo/pdb |
Group deposition | PanDDA analysis group deposition (G_1002265) |
Descriptor | PH-interacting protein, N-[2-(4,5-dimethyl-1,3-thiazol-2-yl)ethyl]-4-(thiophene-2-carbonyl)piperazine-1-carboxamide (3 entities in total) |
Functional Keywords | false negatives, ligand features, rescreening, catalogue, fragment follow-ups, automated chemistry, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 18006.37 |
Authors | Grosjean, H.,Tomlinson, C.,Bradshaw, W.J.,Koekemoer, L.,Krojer, T.,Fearon, D.,Biggin, P.C.,von Delft, F. (deposition date: 2023-03-09, release date: 2023-03-29, Last modification date: 2024-05-22) |
Primary citation | Grosjean, H.,Tomlinson, C.,Bradshaw, W.J.,Koekemoer, L.,Krojer, T.,Fearon, D.,Biggin, P.C.,von Delft, F. PanDDA analysis group deposition To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.19 Å) |
Structure validation
Download full validation report