7FTP
Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(4-chlorophenyl)-10,11-dimethoxy-7-methyl-2,4,6-triazatricyclo[7.3.1.05,13]trideca-1(12),2,4,7,9(13),10-hexaene
Summary for 7FTP
Entry DOI | 10.2210/pdb7ftp/pdb |
Group deposition | To be published (G_1002263) |
Descriptor | Cyclic GMP-AMP synthase, ZINC ION, 4-(4-chlorophenyl)-7,8-dimethoxy-5-methyl-4H-pyrido[2,3,4-de]quinazoline, ... (4 entities in total) |
Functional Keywords | immune response, transferase, ntase, dna sensor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 42824.12 |
Authors | Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Zhang, Z.,Rudolph, M.G. (deposition date: 2023-02-08, release date: 2024-02-21) |
Primary citation | Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G. Crystal Structure of a human cyclic GMP-AMP synthase complex To be published, |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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