7EOK
Crystal structure of the Pepper aptamer in complex with HBC485
Summary for 7EOK
Entry DOI | 10.2210/pdb7eok/pdb |
Descriptor | Pepper (49-MER), GUANOSINE-5'-TRIPHOSPHATE, 4-[(~{Z})-1-cyano-2-[5-[2-(dimethylamino)ethyl-methyl-amino]pyrazin-2-yl]ethenyl]benzenecarbonitrile, ... (5 entities in total) |
Functional Keywords | fluorescent rna, aptamer, hbc485, rna |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 16502.49 |
Authors | Huang, K.Y.,Ren, A.M. (deposition date: 2021-04-22, release date: 2021-11-24, Last modification date: 2023-11-29) |
Primary citation | Huang, K.,Chen, X.,Li, C.,Song, Q.,Li, H.,Zhu, L.,Yang, Y.,Ren, A. Structure-based investigation of fluorogenic Pepper aptamer. Nat.Chem.Biol., 17:1289-1295, 2021 Cited by PubMed: 34725509DOI: 10.1038/s41589-021-00884-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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