7EJK
Structure of the alpha2A-adrenergic receptor GoA signaling complex bound to oxymetazoline
Summary for 7EJK
Entry DOI | 10.2210/pdb7ejk/pdb |
Related | 7EJ8 7EJA 7EL0 |
EMDB information | 31162 |
Descriptor | Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | alpha2a-adrenergic receptor, signaling complex, cryo-em, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 170228.23 |
Authors | |
Primary citation | Xu, J.,Cao, S.,Hubner, H.,Weikert, D.,Chen, G.,Lu, Q.,Yuan, D.,Gmeiner, P.,Liu, Z.,Du, Y. Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor. Sci Adv, 8:eabj5347-eabj5347, 2022 Cited by PubMed: 35245122DOI: 10.1126/sciadv.abj5347 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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