7E9N

Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)

Summary for 7E9N

• Entry DOI: 10.2210/pdb7e9n/pdb
• EMDB information: 31033 31034 31035 31036 31209 31210 31444
• Descriptor: Spike glycoprotein, Light chain of 35B5 Fab, Heavy chain of 35B5 Fab, ... (4 entities in total)
• Functional Keywords: viral protein, immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 9
• Total formula weight: 525255.65

Authors

Wang, X.F.,Zhu, Y.Q. (deposition date: 2021-03-04, release date: 2022-04-06, Last modification date: 2024-11-13)

• Primary citation: Wang, X.,Hu, A.,Chen, X.,Zhang, Y.,Yu, F.,Yue, S.,Li, A.,Zhang, J.,Pan, Z.,Yang, Y.,Lin, Y.,Gao, L.,Zhou, J.,Zhao, J.,Li, F.,Shi, Y.,Huang, F.,Yang, X.,Peng, Y.,Tu, L.,Zhang, H.,Zheng, H.,He, J.,Zhang, H.,Xu, L.,Huang, Q.,Zhu, Y.,Deng, K.,Ye, L.; A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD; Signal Transduct Target Ther, 7:114-, 2022; DOI: 10.1038/s41392-022-00954-8

Experimental method

ELECTRON MICROSCOPY (3.69 Å)