7DUX
Crystal structure of VIM-2 MBL in complex with 1-(but-3-en-1-yl)-1H-imidazole-2-carboxylic acid
Summary for 7DUX
Entry DOI | 10.2210/pdb7dux/pdb |
Descriptor | Beta-lactamase class B VIM-2, ZINC ION, 1-but-3-enylimidazole-2-carboxylic acid, ... (5 entities in total) |
Functional Keywords | metallo-beta-lactamase vim-2, vim-2, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 25068.53 |
Authors | Li, G.-B.,Yan, Y.-H. (deposition date: 2021-01-12, release date: 2022-01-19, Last modification date: 2023-11-29) |
Primary citation | Yan, Y.H.,Li, W.,Chen, W.,Li, C.,Zhu, K.R.,Deng, J.,Dai, Q.Q.,Yang, L.L.,Wang, Z.,Li, G.B. Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 228:113965-113965, 2022 Cited by PubMed: 34763944DOI: 10.1016/j.ejmech.2021.113965 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.981 Å) |
Structure validation
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