7DSQ
Overall structure of the LAT1-4F2hc bound with 3,5-diiodo-L-tyrosine
Summary for 7DSQ
Entry DOI | 10.2210/pdb7dsq/pdb |
EMDB information | 30841 |
Descriptor | 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | lat1-4f2hc, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 131156.76 |
Authors | Yan, R.H.,Li, Y.N.,Zhang, Y.Y.,Zhong, X.Y.,Zhou, Q. (deposition date: 2020-12-31, release date: 2021-03-10, Last modification date: 2022-06-29) |
Primary citation | Yan, R.,Li, Y.,Muller, J.,Zhang, Y.,Singer, S.,Xia, L.,Zhong, X.,Gertsch, J.,Altmann, K.H.,Zhou, Q. Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7:16-16, 2021 Cited by PubMed: 33758168DOI: 10.1038/s41421-021-00247-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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