7C8U

The crystal structure of COVID-19 main protease in complex with GC376

Summary for 7C8U

• Entry DOI: 10.2210/pdb7c8u/pdb
• Descriptor: 3C-like proteinase, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid (3 entities in total)
• Functional Keywords: viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 1
• Total formula weight: 34311.10

Authors

Luan, X.,Shang, W.,Wang, Y.,Yin, W.,Jiang, Y.,Feng, S.,Wang, Y.,Liu, M.,Zhou, R.,Zhang, Z.,Wang, F.,Cheng, W.,Gao, M.,Wang, H.,Wu, W.,Tian, R.,Tian, Z.,Jin, Y.,Jiang, H.W.,Zhang, L.,Xu, H.E.,Zhang, S. (deposition date: 2020-06-03, release date: 2020-06-24, Last modification date: 2023-11-29)

• Primary citation: Zhang, S.Y.,Luan, X.D.,Wang, F.; The crystal structure of COVID-19 main protease in complex with GC376; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)