7BVG
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose.
Summary for 7BVG
Entry DOI | 10.2210/pdb7bvg/pdb |
EMDB information | 30219 |
Descriptor | Integral membrane indolylacetylinositol arabinosyltransferase EmbA, Integral membrane indolylacetylinositol arabinosyltransferase EmbB, Meromycolate extension acyl carrier protein, ... (9 entities in total) |
Functional Keywords | mycobacterium smegmatis, cell wall synthesis, drug target, ethambutol, arabinosyltransferase, emba, embb, embc, acyl carrier protein, arabinogalactan, lipoarabinomannan, drug resistance, transferase |
Biological source | Mycolicibacterium smegmatis MC2 155 More |
Total number of polymer chains | 3 |
Total formula weight | 251038.53 |
Authors | |
Primary citation | Zhang, L.,Zhao, Y.,Gao, Y.,Wu, L.,Gao, R.,Zhang, Q.,Wang, Y.,Wu, C.,Wu, F.,Gurcha, S.S.,Veerapen, N.,Batt, S.M.,Zhao, W.,Qin, L.,Yang, X.,Wang, M.,Zhu, Y.,Zhang, B.,Bi, L.,Zhang, X.,Yang, H.,Guddat, L.W.,Xu, W.,Wang, Q.,Li, J.,Besra, G.S.,Rao, Z. Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368:1211-1219, 2020 Cited by PubMed: 32327601DOI: 10.1126/science.aba9102 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
Download full validation report