7BSV

Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdSer-occluded E2-AlF state

Summary for 7BSV

Entry DOI	10.2210/pdb7bsv/pdb
EMDB information	30168
Descriptor	ATP11C, CDC50A, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	flippase, p-type atpase, p4-atpase, phospholipid, membrane protein
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	167270.75
Authors	Abe, K.,Nishizawa, T.,Nakanishi, H. (deposition date: 2020-03-31, release date: 2020-09-30, Last modification date: 2020-10-14)
Primary citation	Nakanishi, H.,Nishizawa, T.,Segawa, K.,Nureki, O.,Fujiyoshi, Y.,Nagata, S.,Abe, K. Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep, 32:108208-108208, 2020 Cited by PubMed: 32997992 DOI: 10.1016/j.celrep.2020.108208 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation