7B4S

Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and compound 153786 from the NCI Open Database

Summary for 7B4S

Entry DOI	10.2210/pdb7b4s/pdb
Descriptor	Possible 4'-phosphopantetheinyl transferase, 5-[(4-chlorophenyl)methyl]-6-[[2-(dimethylamino)ethylamino]methyl]-4-oxidanyl-1~{H}-pyrimidine-2-thione, COENZYME A, ... (5 entities in total)
Functional Keywords	mycobacterium abscessus 4'-phosphopantetheinyl transferase complex, transferase
Biological source	Mycobacteroides abscessus ATCC 19977
Total number of polymer chains	1
Total formula weight	26662.35
Authors	Maveyraud, L.,Carivenc, C.,Mourey, L. (deposition date: 2020-12-02, release date: 2021-11-10, Last modification date: 2024-01-31)
Primary citation	Carivenc, C.,Maveyraud, L.,Blanger, C.,Ballereau, S.,Roy-Camille, C.,Nguyen, M.C.,Genisson, Y.,Guilhot, C.,Chalut, C.,Pedelacq, J.D.,Mourey, L. Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11:18042-18042, 2021 Cited by PubMed: 34508141 DOI: 10.1038/s41598-021-97197-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.38 Å)

Structure validation