7ANA
A single sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium (BT1622-S1_20)
This is a non-PDB format compatible entry.
Summary for 7ANA
Entry DOI | 10.2210/pdb7ana/pdb |
Related | 7ALL 7ANI 7PV0 7PV1 |
Descriptor | N-acetylgalactosamine-6-sulfatase, 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | carbohydrate sulfatase, mucin, microbiome, bacteroides, hydrolase |
Biological source | Bacteroides thetaiotaomicron VPI-5482 |
Total number of polymer chains | 2 |
Total formula weight | 114457.51 |
Authors | Sofia de Jesus Vaz Luis, A.,Basle, A.,Martens, E.C.,Cartmell, A. (deposition date: 2020-10-11, release date: 2021-11-10, Last modification date: 2024-05-01) |
Primary citation | Luis, A.S.,Jin, C.,Pereira, G.V.,Glowacki, R.W.P.,Gugel, S.R.,Singh, S.,Byrne, D.P.,Pudlo, N.A.,London, J.A.,Basle, A.,Reihill, M.,Oscarson, S.,Eyers, P.A.,Czjzek, M.,Michel, G.,Barbeyron, T.,Yates, E.A.,Hansson, G.C.,Karlsson, N.G.,Cartmell, A.,Martens, E.C. A single sulfatase is required to access colonic mucin by a gut bacterium. Nature, 598:332-337, 2021 Cited by PubMed: 34616040DOI: 10.1038/s41586-021-03967-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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