6ZXQ

Adenylosuccinate Synthetase from H. pylori in complex with HDA, GDP, IMO, Mg

Summary for 6ZXQ

• Entry DOI: 10.2210/pdb6zxq/pdb
• Descriptor: Adenylosuccinate synthetase, HADACIDIN, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: complex, synthetase, n-c ligase, purine salvage pathway, ligase
• Biological source: Helicobacter pylori 26695
• Total number of polymer chains: 1
• Total formula weight: 47895.60

Authors

Bubic, A.,Stefanic, Z. (deposition date: 2020-07-30, release date: 2021-08-11, Last modification date: 2024-02-07)

• Primary citation: Bubic, A.,Narczyk, M.,Petek, A.,Wojtys, M.I.,Maksymiuk, W.,Wielgus-Kutrowska, B.,Winiewska-Szajewska, M.,Pavkov-Keller, T.,Bertosa, B.,Stefanic, Z.,Luic, M.,Bzowska, A.,Lescic Asler, I.; The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site; Int.J.Biol.Macromol., 2023; DOI: 10.1016/j.ijbiomac.2022.12.001

Experimental method

X-RAY DIFFRACTION (1.4 Å)