6ZWE

Crystal structure of human acetylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide)

6ZWE の概要

• エントリーDOI: 10.2210/pdb6zwe/pdb
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: human acetylcholinesterase, piperine derivative, mitochondria, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 123948.93

構造登録者

Da Silva, O.,Dias, J.,Nachon, F.,Brazzolotto, X. (登録日: 2020-07-28, 公開日: 2021-06-09, 最終更新日: 2024-01-31)

• 主引用文献: Chavarria, D.,Da Silva, O.,Benfeito, S.,Barreiro, S.,Garrido, J.,Cagide, F.,Soares, P.,Remiao, F.,Brazzolotto, X.,Nachon, F.,Oliveira, P.J.,Dias, J.,Borges, F.; Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases.; Antioxidants (Basel), 10:-, 2021; PubMed: 33672269; DOI: 10.3390/antiox10020329

実験手法

X-RAY DIFFRACTION (3 Å)