6ZLH

the structure of glutamate transporter homologue GltTk in complex with the photo switchable compound (trans)

6ZLH の概要

• エントリーDOI: 10.2210/pdb6zlh/pdb
• 関連するPDBエントリー: 6ZL4
• 分子名称: Proton/glutamate symporter, SDF family, (2~{S},3~{S})-2-azanyl-3-[[4-[2-(4-methoxyphenyl)hydrazinyl]phenyl]methoxy]butanedioic acid, DECYL-BETA-D-MALTOPYRANOSIDE, ... (8 entities in total)
• 機能のキーワード: glutamate transporter, amino acid transporter, photoisomerization, membrane protein, transport protein
• 由来する生物種: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 146044.49

構造登録者

Arkhipova, V.,Slotboom, D.J.,Guskov, A. (登録日: 2020-06-30, 公開日: 2021-01-27, 最終更新日: 2024-01-31)

• 主引用文献: Arkhipova, V.,Fu, H.,Hoorens, M.W.H.,Trinco, G.,Lameijer, L.N.,Marin, E.,Feringa, B.L.,Poelarends, G.J.,Szymanski, W.,Slotboom, D.J.,Guskov, A.; Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue.; J.Am.Chem.Soc., 143:1513-1520, 2021; PubMed: 33449695; DOI: 10.1021/jacs.0c11336

実験手法

X-RAY DIFFRACTION (2.8 Å)