6ZHY

Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: hexasome class.

6ZHY の概要

• エントリーDOI: 10.2210/pdb6zhy/pdb
• EMDBエントリー: 11221
• 分子名称: Histone H3, Histone H4, Histone H2A type 1, ... (7 entities in total)
• 機能のキーワード: alc1, chd1l, chromatin remodeler, dna damage response, nucleosome, hexasome, nuclear protein, gene regulation, dna binding protein
• 由来する生物種: Xenopus laevis (African clawed frog); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 174946.08

構造登録者

Bacic, L.,Gaullier, G.,Deindl, S. (登録日: 2020-06-24, 公開日: 2020-12-23, 最終更新日: 2021-07-14)

• 主引用文献: Lehmann, L.C.,Bacic, L.,Hewitt, G.,Brackmann, K.,Sabantsev, A.,Gaullier, G.,Pytharopoulou, S.,Degliesposti, G.,Okkenhaug, H.,Tan, S.,Costa, A.,Skehel, J.M.,Boulton, S.J.,Deindl, S.; Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.; Cell Rep, 33:108529-108529, 2020; PubMed: 33357431; DOI: 10.1016/j.celrep.2020.108529

実験手法

ELECTRON MICROSCOPY (3 Å)