6ZHA
Cryo-EM structure of DNA-PK monomer
Summary for 6ZHA
Entry DOI | 10.2210/pdb6zha/pdb |
EMDB information | 11217 |
Descriptor | DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (5 entities in total) |
Functional Keywords | kinase, dna-pkcs, nhej, dna-repair, dna-pk, dna binding protein, ku70/80 |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 639888.61 |
Authors | Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2020-06-21, release date: 2020-10-21, Last modification date: 2024-05-01) |
Primary citation | Chaplin, A.K.,Hardwick, S.W.,Liang, S.,Kefala Stavridi, A.,Hnizda, A.,Cooper, L.R.,De Oliveira, T.M.,Chirgadze, D.Y.,Blundell, T.L. Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28:13-19, 2021 Cited by PubMed: 33077952DOI: 10.1038/s41594-020-00517-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.91 Å) |
Structure validation
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