6ZHA

Cryo-EM structure of DNA-PK monomer

6ZHA の概要

• エントリーDOI: 10.2210/pdb6zha/pdb
• EMDBエントリー: 11217
• 分子名称: DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (5 entities in total)
• 機能のキーワード: kinase, dna-pkcs, nhej, dna-repair, dna-pk, dna binding protein, ku70/80
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 639888.61

構造登録者

Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. (登録日: 2020-06-21, 公開日: 2020-10-21, 最終更新日: 2024-05-01)

• 主引用文献: Chaplin, A.K.,Hardwick, S.W.,Liang, S.,Kefala Stavridi, A.,Hnizda, A.,Cooper, L.R.,De Oliveira, T.M.,Chirgadze, D.Y.,Blundell, T.L.; Dimers of DNA-PK create a stage for DNA double-strand break repair.; Nat.Struct.Mol.Biol., 28:13-19, 2021; PubMed: 33077952; DOI: 10.1038/s41594-020-00517-x

実験手法

ELECTRON MICROSCOPY (3.91 Å)