6ZFS

Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor WDH-1U-4

6ZFS の概要

• エントリーDOI: 10.2210/pdb6zfs/pdb
• 分子名称: Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 9, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ... (22 entities in total)
• 機能のキーワード: cytochrome bc1, malaria, electron transport
• 由来する生物種: Bos taurus (cattle); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 239155.26

構造登録者

Amporndanai, K.,O'Neill, P.M.,Hong, W.D.,Amewu, R.K.,Pidathala, C.,Berry, N.G.,Biagini, G.A.,Leung, S.C.,Hasnain, S.S.,Antonyuk, S.V. (登録日: 2020-06-17, 公開日: 2021-06-30, 最終更新日: 2024-01-24)

• 主引用文献: Amporndanai, K.,O'Neill, P.M.,Hong, W.D.,Amewu, R.K.,Pidathala, C.,Berry, N.,Biangini, G.A.,Leung, S.C.,Hasnain, S.S.,Antonyuk, S.V.; Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials; To Be Published,

実験手法

X-RAY DIFFRACTION (3.5 Å)