6ZEP

Flavourzyme Leucine Aminopeptidase A proenzyme

Summary for 6ZEP

• Entry DOI: 10.2210/pdb6zep/pdb
• Descriptor: Leucine aminopeptidase A, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
• Functional Keywords: m28 peptidase, prodomain, intramolecular chaperone, bimetallic aminopeptidase, hydrolase
• Biological source: Aspergillus oryzae (strain ATCC 42149 / RIB 40)
• Total number of polymer chains: 1
• Total formula weight: 42777.30

Authors

Watson, K.A.,Baltulionis, G. (deposition date: 2020-06-16, release date: 2021-06-16, Last modification date: 2024-01-24)

• Primary citation: Baltulionis, G.,Blight, M.,Robin, A.,Charalampopoulos, D.,Watson, K.A.; The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase.; J.Struct.Biol., 213:107741-107741, 2021; PubMed: 33989771; DOI: 10.1016/j.jsb.2021.107741

Experimental method

X-RAY DIFFRACTION (1.61 Å)