6ZEC

Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody

Summary for 6ZEC

• Entry DOI: 10.2210/pdb6zec/pdb
• Descriptor: Fab fragment light chain, Fab fragment heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: antibody, fab, glycosylated, glycans, lymphoma, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 50686.71

Authors

Allen, J.D.,Watanabe, Y.,Crispin, M.,Bowden, T.A. (deposition date: 2020-06-16, release date: 2021-06-30, Last modification date: 2024-01-24)

• Primary citation: Chiodin, G.,Allen, J.D.,Bryant, D.J.,Rock, P.,Martino, E.A.,Valle-Argos, B.,Duriez, P.J.,Watanabe, Y.,Henderson, I.,Blachly, J.S.,McCann, K.J.,Strefford, J.C.,Packham, G.,Geijtenbeek, T.B.H.,Figdor, C.G.,Wright, G.W.,Staudt, L.M.,Burack, R.,Bowden, T.A.,Crispin, M.,Stevenson, F.K.,Forconi, F.; Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior.; Blood, 138:1570-1582, 2021; PubMed: 34424958; DOI: 10.1182/blood.2021012052

Experimental method

X-RAY DIFFRACTION (1.65 Å)