6Z8G

Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure.

Summary for 6Z8G

• Entry DOI: 10.2210/pdb6z8g/pdb
• Descriptor: Variant surface glycoprotein MITat 1.13, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... (5 entities in total)
• Functional Keywords: variant surface glycoprotein, immune recognition, immune evasion, trypanosomiasis, membrane protein
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 110974.04

Authors

Stebbins, C.E.,Hempelmann, A.,Van Straaten, M.,Zeelen, J. (deposition date: 2020-06-02, release date: 2021-03-17)

• Primary citation: Zeelen, J.,van Straaten, M.,Verdi, J.,Hempelmann, A.,Hashemi, H.,Perez, K.,Jeffrey, P.D.,Halg, S.,Wiedemar, N.,Maser, P.,Papavasiliou, F.N.,Stebbins, C.E.; Structure of trypanosome coat protein VSGsur and function in suramin resistance.; Nat Microbiol, 6:392-400, 2021; PubMed: 33462435; DOI: 10.1038/s41564-020-00844-1

Experimental method

X-RAY DIFFRACTION (1.56 Å)