6Z8G

Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure.

6Z8G の概要

• エントリーDOI: 10.2210/pdb6z8g/pdb
• 分子名称: Variant surface glycoprotein MITat 1.13, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... (5 entities in total)
• 機能のキーワード: variant surface glycoprotein, immune recognition, immune evasion, trypanosomiasis, membrane protein
• 由来する生物種: Trypanosoma brucei
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 110974.04

構造登録者

Stebbins, C.E.,Hempelmann, A.,Van Straaten, M.,Zeelen, J. (登録日: 2020-06-02, 公開日: 2021-03-17)

• 主引用文献: Zeelen, J.,van Straaten, M.,Verdi, J.,Hempelmann, A.,Hashemi, H.,Perez, K.,Jeffrey, P.D.,Halg, S.,Wiedemar, N.,Maser, P.,Papavasiliou, F.N.,Stebbins, C.E.; Structure of trypanosome coat protein VSGsur and function in suramin resistance.; Nat Microbiol, 6:392-400, 2021; PubMed: 33462435; DOI: 10.1038/s41564-020-00844-1

実験手法

X-RAY DIFFRACTION (1.56 Å)