6Z56

Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003208

6Z56 の概要

• エントリーDOI: 10.2210/pdb6z56/pdb
• 分子名称: Serine/threonine-protein kinase haspin, 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, DIMETHYL SULFOXIDE, ... (4 entities in total)
• 機能のキーワード: kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41230.11

構造登録者

Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2020-05-26, 公開日: 2020-06-03, 最終更新日: 2024-01-24)

• 主引用文献: Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003208; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)