6Z2S

Crystal structure of adhibin analogue-bound myosin-2

Summary for 6Z2S

• Entry DOI: 10.2210/pdb6z2s/pdb
• Descriptor: Myosin-2 heavy chain, MAGNESIUM ION, 3,6-dibromo-1-(hydroxymethyl)carbazole, ... (7 entities in total)
• Functional Keywords: myosin, inhibitor, adhibin analogue, carbazole, pre-powerstroke state, hydrolase, motor protein
• Biological source: Dictyostelium discoideum
• Total number of polymer chains: 1
• Total formula weight: 91558.64

Authors

Ewert, W.,Knoelker, H.-J.,Tsiavaliaris, G.,Preller, M. (deposition date: 2020-05-18, release date: 2021-06-09, Last modification date: 2024-01-24)

• Primary citation: Bader, A.,Ewert, W.,Knoelker, H.-J.,Preller, M.,Tsiavaliaris, G.; The synthetic carbazole adhibin acts as selective myosin class-IX inhibitor in lung cancer cells; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.2 Å)