6Z1O

AL amyloid fibril from a lambda 3 light chain in conformation A

Summary for 6Z1O

• Entry DOI: 10.2210/pdb6z1o/pdb
• Related: 6IC3
• EMDB information: 11031 4452
• Descriptor: lambda 3 immunoglobulin light chain fragment, residues 2-116 (1 entity in total)
• Functional Keywords: amyloid, antibody, systemic amyloidosis, light chain, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 56587.82

Authors

Radamaker, L.,Fandrich, M. (deposition date: 2020-05-14, release date: 2021-02-24)

• Primary citation: Radamaker, L.,Baur, J.,Huhn, S.,Haupt, C.,Hegenbart, U.,Schonland, S.,Bansal, A.,Schmidt, M.,Fandrich, M.; Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis.; Nat Commun, 12:875-875, 2021; PubMed: 33558536; DOI: 10.1038/s41467-021-21126-2

Experimental method

ELECTRON MICROSCOPY (3.2 Å)