6Z0O

Structure of Affimer-NP bound to Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Protein

6Z0O の概要

• エントリーDOI: 10.2210/pdb6z0o/pdb
• 関連するPDBエントリー: 4AKL
• 分子名称: Nucleocapsid, Affimer-NP (3 entities in total)
• 機能のキーワード: crimean-congo hemorrhagic fever virus nucleoprotein, affimer-np, complex, high-affinity, anti-viral, rna-binding, viral protein
• 由来する生物種: Crimean-Congo hemorrhagic fever orthonairovirus; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 129805.86

構造登録者

Alvarez-Rodriguez, B.,Tiede, C.,Trinh, C.,Tomlinson, D.,Edwards, T.A.,Barr, J.N. (登録日: 2020-05-10, 公開日: 2020-05-27, 最終更新日: 2024-01-24)

• 主引用文献: Alvarez-Rodriguez, B.,Tiede, C.,Hoste, A.C.R.,Surtees, R.A.,Trinh, C.H.,Slack, G.S.,Chamberlain, J.,Hewson, R.,Fresco, A.,Sastre, P.,Tomlinson, D.C.,Millner, P.A.,Edwards, T.A.,Barr, J.N.; Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests.; Plos Negl Trop Dis, 14:e0008364-e0008364, 2020; PubMed: 32492018; DOI: 10.1371/journal.pntd.0008364

実験手法

X-RAY DIFFRACTION (2.5974 Å)