6YR7

14-3-3 sigma in complex with hDMX-342+367 peptide

Summary for 6YR7

• Entry DOI: 10.2210/pdb6yr7/pdb
• Related: 6YR5 6YR6
• Descriptor: 14-3-3 protein sigma, Protein Mdm4, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• Functional Keywords: bivalent binding mode, 1433, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 62427.85

Authors

Wolter, M.,Srdanovic, S.,Warriner, S.,Wilson, A.,Ottmann, C. (deposition date: 2020-04-19, release date: 2021-11-03, Last modification date: 2024-01-24)

• Primary citation: Srdanovic, S.,Wolter, M.,Trinh, C.H.,Ottmann, C.,Warriner, S.L.,Wilson, A.J.; Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study.; Febs J., 2022; PubMed: 35286747; DOI: 10.1111/febs.16433

Experimental method

X-RAY DIFFRACTION (2.105 Å)