6YR7
14-3-3 sigma in complex with hDMX-342+367 peptide
Summary for 6YR7
Entry DOI | 10.2210/pdb6yr7/pdb |
Related | 6YR5 6YR6 |
Descriptor | 14-3-3 protein sigma, Protein Mdm4, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | bivalent binding mode, 1433, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 62427.85 |
Authors | Wolter, M.,Srdanovic, S.,Warriner, S.,Wilson, A.,Ottmann, C. (deposition date: 2020-04-19, release date: 2021-11-03, Last modification date: 2024-01-24) |
Primary citation | Srdanovic, S.,Wolter, M.,Trinh, C.H.,Ottmann, C.,Warriner, S.L.,Wilson, A.J. Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study. Febs J., 2022 Cited by PubMed: 35286747DOI: 10.1111/febs.16433 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.105 Å) |
Structure validation
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