6YPG
Crystal Structure of CK2alpha with Compound 2 bound to second crystal form
Summary for 6YPG
| Entry DOI | 10.2210/pdb6ypg/pdb |
| Descriptor | Casein kinase II subunit alpha, 4-[(4-naphthalen-2-yl-1,3-thiazol-2-yl)amino]-2-oxidanyl-benzoic acid, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | selective atp competitive inhibitors, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 39452.84 |
| Authors | Brear, P.,Hyvonen, M. (deposition date: 2020-04-16, release date: 2020-07-15, Last modification date: 2024-01-24) |
| Primary citation | Brear, P.,Ball, D.,Stott, K.,D'Arcy, S.,Hyvonen, M. Proposed Allosteric Inhibitors Bind to the ATP Site of CK2 alpha. J.Med.Chem., 63:12786-12798, 2020 Cited by PubMed: 33119282DOI: 10.1021/acs.jmedchem.0c01173 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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