6YNN
Crystal structure of YTHDC1 with compound DHU_DC1_135
Summary for 6YNN
Entry DOI | 10.2210/pdb6ynn/pdb |
Descriptor | YTHDC1, 6-[[(2-chloranyl-6-fluoranyl-phenyl)methyl-methyl-amino]methyl]-1~{H}-pyrimidine-2,4-dione, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ythdc1, m6a, complex, inhibitor, rna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 43202.19 |
Authors | Bedi, R.K.,Huang, D.,Wiedmer, L.,Caflisch, A. (deposition date: 2020-04-14, release date: 2020-07-15, Last modification date: 2024-01-24) |
Primary citation | Li, Y.,Bedi, R.K.,Wiedmer, L.,Sun, X.,Huang, D.,Caflisch, A. Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17:1240-1249, 2021 Cited by PubMed: 33472367DOI: 10.1021/acs.jctc.0c01136 PDB entries with the same primary citation |
Experimental method |
Structure validation
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