6YN2
Crystal structure of Renilla reniformis luciferase variant RLuc8-W121F/E144Q in complex with a coelenteramide (the postcatalytic enzyme-product complex)
Summary for 6YN2
Entry DOI | 10.2210/pdb6yn2/pdb |
Descriptor | Coelenterazine h 2-monooxygenase, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, ACETATE ION, ... (6 entities in total) |
Functional Keywords | bioluminscence, coelenteramide-bound enzyme, luminescent protein |
Biological source | Renilla reniformis (Sea pansy) |
Total number of polymer chains | 2 |
Total formula weight | 74827.45 |
Authors | Damborsky, J.,Marek, M. (deposition date: 2020-04-10, release date: 2021-04-21, Last modification date: 2024-01-24) |
Primary citation | Schenkmayerova, A.,Pinto, G.P.,Toul, M.,Marek, M.,Hernychova, L.,Planas-Iglesias, J.,Daniel Liskova, V.,Pluskal, D.,Vasina, M.,Emond, S.,Dorr, M.,Chaloupkova, R.,Bednar, D.,Prokop, Z.,Hollfelder, F.,Bornscheuer, U.T.,Damborsky, J. Engineering the protein dynamics of an ancestral luciferase. Nat Commun, 12:3616-3616, 2021 Cited by PubMed: 34127663DOI: 10.1038/s41467-021-23450-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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