6YN2

Crystal structure of Renilla reniformis luciferase variant RLuc8-W121F/E144Q in complex with a coelenteramide (the postcatalytic enzyme-product complex)

6YN2 の概要

• エントリーDOI: 10.2210/pdb6yn2/pdb
• 分子名称: Coelenterazine h 2-monooxygenase, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, ACETATE ION, ... (6 entities in total)
• 機能のキーワード: bioluminscence, coelenteramide-bound enzyme, luminescent protein
• 由来する生物種: Renilla reniformis (Sea pansy)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74827.45

構造登録者

Damborsky, J.,Marek, M. (登録日: 2020-04-10, 公開日: 2021-04-21, 最終更新日: 2024-01-24)

• 主引用文献: Schenkmayerova, A.,Pinto, G.P.,Toul, M.,Marek, M.,Hernychova, L.,Planas-Iglesias, J.,Daniel Liskova, V.,Pluskal, D.,Vasina, M.,Emond, S.,Dorr, M.,Chaloupkova, R.,Bednar, D.,Prokop, Z.,Hollfelder, F.,Bornscheuer, U.T.,Damborsky, J.; Engineering the protein dynamics of an ancestral luciferase.; Nat Commun, 12:3616-3616, 2021; PubMed: 34127663; DOI: 10.1038/s41467-021-23450-z

実験手法

X-RAY DIFFRACTION (1.9 Å)