6YI0
Human histidine triad nucleotide-binding protein 2 (hHINT2) refined to 1.65 A in P41212 space group
This is a non-PDB format compatible entry.
Replaces: 4NJXSummary for 6YI0
| Entry DOI | 10.2210/pdb6yi0/pdb |
| Descriptor | Histidine triad nucleotide-binding protein 2, mitochondrial, SODIUM ION (3 entities in total) |
| Functional Keywords | nucleotide binding protein, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 68757.89 |
| Authors | Dolot, R.D.,Wlodarczyk, A.,Bujacz, G.D.,Nawrot, B.C. (deposition date: 2020-03-31, release date: 2020-04-29, Last modification date: 2024-01-24) |
| Primary citation | Dolot, R.,Krakowiak, A.,Kaczmarek, R.,Wlodarczyk, A.,Pichlak, M.,Nawrot, B. Biochemical, crystallographic and biophysical characterization of histidine triad nucleotide-binding protein 2 with different ligands including a non-hydrolyzable analog of Ap4A. Biochim Biophys Acta Gen Subj, 1865:129968-129968, 2021 Cited by PubMed Abstract: Human HINT2 is an important mitochondrial enzyme involved in many processes such as apoptosis and bioenergetics, but its endogenous substrates and the three-dimensional structure of the full-length protein have not been identified yet. PubMed: 34329705DOI: 10.1016/j.bbagen.2021.129968 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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