6YE9

Small-molecule inhibitor of 14-3-3 protein-protein interactions

6YE9 の概要

• エントリーDOI: 10.2210/pdb6ye9/pdb
• 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, [2-[2-oxidanylidene-2-[(phenylmethyl)amino]ethoxy]phenyl]phosphonic acid, ... (4 entities in total)
• 機能のキーワード: 14-3-3, inhibitor, protein-protein interaction, small molecule, structural protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26937.09

構造登録者

Ottmann, C.,Visser, E.J. (登録日: 2020-03-24, 公開日: 2021-03-31, 最終更新日: 2024-01-24)

• 主引用文献: Sijbesma, E.,Visser, E.J.,Plitzko, K.,Thiel, P.,Milroy, L.G.,Kaiser, M.,Brunsveld, L.,Ottmann, C.; Structure-based conversion of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)