6YCP

Crystal structure of GcoA F169V bound to o-vanillin

6YCP の概要

• エントリーDOI: 10.2210/pdb6ycp/pdb
• 分子名称: Aromatic O-demethylase, cytochrome P450 subunit, PROTOPORPHYRIN IX CONTAINING FE, 2-(hydroxymethyl)-6-methoxy-phenol, ... (4 entities in total)
• 機能のキーワード: aromatic catabolism, cytochrome p450, lignin valorization, protein engineering, oxidoreductase
• 由来する生物種: Amycolatopsis sp. (strain ATCC 39116 / 75iv2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46175.38

構造登録者

Hinchen, D.J.,Mallinson, S.J.B.,Allen, M.D.,Ellis, E.S.,Beckham, G.T.,DuBois, J.L.,McGeehan, J.E. (登録日: 2020-03-18, 公開日: 2021-02-17, 最終更新日: 2024-01-24)

• 主引用文献: Ellis, E.S.,Hinchen, D.J.,Bleem, A.,Bu, L.,Mallinson, S.J.B.,Allen, M.D.,Streit, B.R.,Machovina, M.M.,Doolin, Q.V.,Michener, W.E.,Johnson, C.W.,Knott, B.C.,Beckham, G.T.,McGeehan, J.E.,DuBois, J.L.; Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes.; Jacs Au, 1:252-261, 2021; PubMed: 34467290; DOI: 10.1021/jacsau.0c00103

実験手法

X-RAY DIFFRACTION (1.8 Å)