6Y7F

Crystal structure of human ELOVL fatty acid elongase 7 (ELOVL7)

Summary for 6Y7F

• Entry DOI: 10.2210/pdb6y7f/pdb
• Descriptor: Elongation of very long chain fatty acids protein 7, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-oxidanylideneicosanethioate, Octyl Glucose Neopentyl Glycol, ... (5 entities in total)
• Functional Keywords: fatty acid biosynthesis, lipid biosynthesis, membrane protein, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 73014.08

Authors

Nie, L.,Pike, A.C.W.,Bushell, S.R.,Chu, A.,Cole, V.,Speedman, D.,Rodstrom, K.E.J.,Kupinska, K.,Shrestha, L.,Mukhopadhyay, S.M.M.,Burgess-Brown, N.A.,Love, J.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2020-02-28, release date: 2020-05-13, Last modification date: 2024-11-13)

• Primary citation: Nie, L.,Pike, A.C.W.,Bushell, S.R.,Chu, A.,Cole, V.,Speedman, D.,Kupinska, K.,Shrestha, L.,Mukhopadhyay, S.M.M.,Burgess-Brown, N.A.,Love, J.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Carpenter, E.P.; Crystal structure of human ELOVL fatty acid elongase 7 (ELOVL7); TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.052 Å)