6Y2E
Crystal structure of the free enzyme of the SARS-CoV-2 (2019-nCoV) main protease
Summary for 6Y2E
Entry DOI | 10.2210/pdb6y2e/pdb |
Descriptor | 3C-like proteinase (2 entities in total) |
Functional Keywords | novel coronavirus, alpha-ketoamide, antiviral, drug design, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 1 |
Total formula weight | 33825.55 |
Authors | Zhang, L.,Sun, X.,Hilgenfeld, R. (deposition date: 2020-02-15, release date: 2020-03-04, Last modification date: 2024-01-24) |
Primary citation | Zhang, L.,Lin, D.,Sun, X.,Curth, U.,Drosten, C.,Sauerhering, L.,Becker, S.,Rox, K.,Hilgenfeld, R. Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors. Science, 368:409-412, 2020 Cited by PubMed: 32198291DOI: 10.1126/science.abb3405 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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