6Y1A
Amyloid fibril structure of islet amyloid polypeptide
Summary for 6Y1A
Entry DOI | 10.2210/pdb6y1a/pdb |
EMDB information | 10669 |
Descriptor | Islet amyloid polypeptide, AMINO GROUP (2 entities in total) |
Functional Keywords | amylin, iapp, amyloid fibril, diabetes, hormone |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 16 |
Total formula weight | 62805.23 |
Authors | Roeder, C.,Kupreichyk, T.,Gremer, L.,Schaefer, L.U.,Pothula, K.R.,Ravelli, R.B.G.,Willbold, D.,Hoyer, W.,Schroder, G.F. (deposition date: 2020-02-11, release date: 2020-03-04, Last modification date: 2020-07-22) |
Primary citation | Roder, C.,Kupreichyk, T.,Gremer, L.,Schafer, L.U.,Pothula, K.R.,Ravelli, R.B.G.,Willbold, D.,Hoyer, W.,Schroder, G.F. Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-beta fibrils. Nat.Struct.Mol.Biol., 27:660-667, 2020 Cited by PubMed: 32541895DOI: 10.1038/s41594-020-0442-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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