6Y08

Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole

Summary for 6Y08

• Entry DOI: 10.2210/pdb6y08/pdb
• Descriptor: Thymidylate synthase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Sulfamethoxazole, ... (4 entities in total)
• Functional Keywords: fragment screening, fragment, inhibitor, thymidylate synthase, transferase
• Biological source: Mus musculus (House mouse)
• Total number of polymer chains: 2
• Total formula weight: 71124.95

Authors

Maj, P.,Jarmula, A.,Wilk, P.,Weiss, M.S.,Rode, W. (deposition date: 2020-02-06, release date: 2021-02-17, Last modification date: 2024-01-24)

• Primary citation: Maj, P.,Jarmula, A.,Wilk, P.,Weiss, M.S.,Rode, W.; Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.297 Å)