6XZ2

Crystal structure of E. Coli purine nucleoside phosphorylase mutant Y160W with SO4 and Formycin A

6XZ2 の概要

• エントリーDOI: 10.2210/pdb6xz2/pdb
• 分子名称: Purine nucleoside phosphorylase DeoD-type, SULFATE ION, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ... (4 entities in total)
• 機能のキーワード: trimer of dimers, single tryptophan mutant, protein-inhibitor complex, transferase
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 77789.43

構造登録者

Narczyk, M.,Bzowska, A. (登録日: 2020-01-31, 公開日: 2021-02-10, 最終更新日: 2024-01-24)

• 主引用文献: Narczyk, M.,Mioduszewski, L.,Oksiejuk, A.,Winiewska-Szajewska, M.,Wielgus-Kutrowska, B.,Gojdz, A.,Ciesla, J.,Bzowska, A.; Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent.; Sci Rep, 11:11144-11144, 2021; PubMed: 34045551; DOI: 10.1038/s41598-021-90472-4

実験手法

X-RAY DIFFRACTION (1.65000304482 Å)