6XYU

Update of AChE from Drosophila Melanogaster complex with tacrine derivative 9-(3-iodobenzylamino)-1,2,3,4-tetrahydroacridine

「1QON」から置き換えられました

6XYU の概要

• エントリーDOI: 10.2210/pdb6xyu/pdb
• 関連するPDBエントリー: 6xys
• 分子名称: Acetylcholinesterase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE, ... (5 entities in total)
• 機能のキーワード: acetylcholinesterase, insect, inhibitor, complex, hydrolase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65782.00

構造登録者

Nachon, F.,Sussman, J.L. (登録日: 2020-01-31, 公開日: 2020-03-18, 最終更新日: 2024-01-24)

• 主引用文献: Nachon, F.,Rosenberry, T.L.,Silman, I.,Sussman, J.L.; A Second Look at the Crystal Structures ofDrosophila melanogasterAcetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides.; Molecules, 25:-, 2020; PubMed: 32155891; DOI: 10.3390/molecules25051198

実験手法

X-RAY DIFFRACTION (2.51 Å)