6XXY
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with O-isobutenyl oxalylhydroxamate.
Summary for 6XXY
Entry DOI | 10.2210/pdb6xxy/pdb |
Descriptor | 3-isopropylmalate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | haemophilus influenzae, leucine biosynthetis, 3-isopropylmalate dehydrogenase, inhibitor, oxidoreductase |
Biological source | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
Total number of polymer chains | 2 |
Total formula weight | 79388.39 |
Authors | Miggiano, R.,Rossi, F.,Martignon, S.,Rizzi, M. (deposition date: 2020-01-28, release date: 2020-02-26, Last modification date: 2024-01-24) |
Primary citation | Miggiano, R.,Martignon, S.,Minassi, A.,Rossi, F.,Rizzi, M. Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate. Biochem.Biophys.Res.Commun., 524:996-1002, 2020 Cited by PubMed: 32059844DOI: 10.1016/j.bbrc.2020.02.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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