6XXN

Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen

6XXN の概要

• エントリーDOI: 10.2210/pdb6xxn/pdb
• 分子名称: NB_7_a,b,c,f, NB_7_g, NB_7_h, ... (5 entities in total)
• 機能のキーワード: nanobody, prostate specific membrane, antigen, antibody drug conjugate, cancer imaging, anti-cancer drugs, antitumor protein
• 由来する生物種: Camelus dromedarius (Arabian camel); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 130538.01

構造登録者

Shahar, A.,Rosenfeld, L.,Papo, N. (登録日: 2020-01-28, 公開日: 2020-06-10, 最終更新日: 2024-01-24)

• 主引用文献: Rosenfeld, L.,Sananes, A.,Zur, Y.,Cohen, S.,Dhara, K.,Gelkop, S.,Ben Zeev, E.,Shahar, A.,Lobel, L.,Akabayov, B.,Arbely, E.,Papo, N.; Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer.; J.Med.Chem., 63:7601-7615, 2020; PubMed: 32442375; DOI: 10.1021/acs.jmedchem.0c00418

実験手法

X-RAY DIFFRACTION (2.65 Å)