6XWM
Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation
Summary for 6XWM
Entry DOI | 10.2210/pdb6xwm/pdb |
Descriptor | Na(+):neurotransmitter symporter (Snf family), PHENYLALANINE, SODIUM ION, ... (4 entities in total) |
Functional Keywords | neurotransmitter:sodium symporters (nss), membrane protein |
Biological source | Aquifex aeolicus VF5 |
Total number of polymer chains | 2 |
Total formula weight | 116346.96 |
Authors | Boesen, T.,Nissen, P.,Gotfryd, K.,Loland, C.J.,Gether, U. (deposition date: 2020-01-24, release date: 2020-05-06, Last modification date: 2024-01-24) |
Primary citation | Gotfryd, K.,Boesen, T.,Mortensen, J.S.,Khelashvili, G.,Quick, M.,Terry, D.S.,Missel, J.W.,LeVine, M.V.,Gourdon, P.,Blanchard, S.C.,Javitch, J.A.,Weinstein, H.,Loland, C.J.,Nissen, P.,Gether, U. X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nat Commun, 11:1005-1005, 2020 Cited by PubMed: 32081981DOI: 10.1038/s41467-020-14735-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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