6XWM

Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation

6XWM の概要

• エントリーDOI: 10.2210/pdb6xwm/pdb
• 分子名称: Na(+):neurotransmitter symporter (Snf family), PHENYLALANINE, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: neurotransmitter:sodium symporters (nss), membrane protein
• 由来する生物種: Aquifex aeolicus VF5
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 116346.96

構造登録者

Boesen, T.,Nissen, P.,Gotfryd, K.,Loland, C.J.,Gether, U. (登録日: 2020-01-24, 公開日: 2020-05-06, 最終更新日: 2024-01-24)

• 主引用文献: Gotfryd, K.,Boesen, T.,Mortensen, J.S.,Khelashvili, G.,Quick, M.,Terry, D.S.,Missel, J.W.,LeVine, M.V.,Gourdon, P.,Blanchard, S.C.,Javitch, J.A.,Weinstein, H.,Loland, C.J.,Nissen, P.,Gether, U.; X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release.; Nat Commun, 11:1005-1005, 2020; PubMed: 32081981; DOI: 10.1038/s41467-020-14735-w

実験手法

X-RAY DIFFRACTION (2.6 Å)