6XUK

AbLIFT design 15 of Ab 1116NS19.9

Summary for 6XUK

Entry DOI	10.2210/pdb6xuk/pdb
Descriptor	Heavy chain, Light chain, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	pancreatic cancer, diagnosis, in-silico optimized antibody, ca19-9 binder, immunotherapeutic reagent, antitumor protein
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	48570.12
Authors	Diskin, R.,Borenstein-Katz, A. (deposition date: 2020-01-20, release date: 2021-02-03, Last modification date: 2024-02-07)
Primary citation	Borenstein-Katz, A.,Warszawski, S.,Amon, R.,Eilon, M.,Cohen-Dvashi, H.,Leviatan Ben-Arye, S.,Tasnima, N.,Yu, H.,Chen, X.,Padler-Karavani, V.,Fleishman, S.J.,Diskin, R. Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies. J.Mol.Biol., 433:167099-167099, 2021 Cited by PubMed: 34119488 DOI: 10.1016/j.jmb.2021.167099 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation