6XTA

Recombinant human butyrylcholinesterase in complex with (2S)-N-[2-(1-benzylazepan-4-yl)ethyl]-2-(butylamino)-3-(1H-indol-3-yl)propanamide

6XTA の概要

• エントリーDOI: 10.2210/pdb6xta/pdb
• 分子名称: Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: butyrylcholinesterase, inhibitor, complex, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62587.83

構造登録者

Brazzolotto, X.,Nachon, F.,Meden, A.,Knez, D.,Gobec, S. (登録日: 2020-01-15, 公開日: 2020-10-28, 最終更新日: 2024-01-24)

• 主引用文献: Meden, A.,Knez, D.,Malikowska-Racia, N.,Brazzolotto, X.,Nachon, F.,Svete, J.,Salat, K.,Groselj, U.,Gobec, S.; Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors.; Eur.J.Med.Chem., 208:112766-112766, 2020; PubMed: 32919297; DOI: 10.1016/j.ejmech.2020.112766

実験手法

X-RAY DIFFRACTION (2.5 Å)