6XR3
X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A
Summary for 6XR3
Entry DOI | 10.2210/pdb6xr3/pdb |
Related | 6W63 6WNP |
Descriptor | 3C-like proteinase, N-[(2S)-1-({(1S,2S)-1-(1,3-benzothiazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide (3 entities in total) |
Functional Keywords | inhibitor, main protease, mpro, 3c-like, 3clpro, sars-cov-2, covid-19, nsp5, structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 1 |
Total formula weight | 34403.24 |
Authors | Anson, B.,Ghosh, A.K.,Mesecar, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-07-10, release date: 2020-08-19, Last modification date: 2023-10-18) |
Primary citation | Anson, B.,Ghosh, A.K.,Mesecar, A. X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
Download full validation report